Our appearance, behavior patterns, and the way we perceive the world are all influenced by a combination of our lifestyle and our genes. The root cause for certain diseases has been proven to be hereditary. In a nutshell, genes are a treasure box of our strengths and weakness. Defects in our genes can have a huge impact on how our body functions. The MTHFR genetic defect falls into such a category, and it affects a considerable amount of adults.

The MTHFR gene controls the production of an enzyme called Methylenetetrahydrofolate reductase. It regulates important process in the body like converting folate into the active form your body uses, amino acid balance, regulation of gene expression, and DNA synthesis. The conversion of inactive folate to an active form so that cells can absorb the enzyme is important, since it is responsible for metabolism.

What Are the Effects Of MTHFR Gene Mutation?

MTHFR gene mutation stunts the ability to process folic acid or vitamin B9. Deficient levels of vitamin B9 can cause a growing fetus to develop devastating neural tube defects. If inactive vitamin B9 is not converted to an active form, metabolic processes like cell division and heart function are affected to a great extent.

Symptoms of MTHFR Gene Mutation

It is an ongoing discussion on how the MTHFR gene mutation affects our health. But strong evidence suggests that the following are tied to primary forms of genetic MTHFR mutation:

• Childhood learning developmental problems

• Depression and anxiety

• Bipolar disorder

• Autoimmune disorders and thyroid disorders

• Migraines

• Hormonal problems and fertility problems that include PCOS and sometimes miscarriages

The severity and type of symptoms that someone experiences depends on the variant of the mutation the person has.


Homocysteine, an amino acid, can cause strokes, cardiovascular disease, the formation of blood clots, and other health issues when it is at a higher level in the blood. When the metabolism is lowered, there is a risk of higher levels of homocysteine. MTHFR mutations can affect the metabolism in this way, and so being aware of these defects is very important.

SpectraCell MTHFR Genotyping

SpectraCell MTHFR genotyping determines the MTHFR genotype and gives important information about an individual’s ability to convert inactive vitamin B9. It is a simple blood test that aids in formulating a plan and adapting processes to address the issue.

Since the problem is related to an inherited gene, a permanent cure is not available. But natural treatments and lifestyle changes help to reduce the risks and complications involved. Physicians provide dietary and medical recommendations, which includes increased intake of folate combined with vitamins B6 and B12.

Who Should Undergo SpectraCell MTHFR Genotyping?

• Individuals with high homocysteine levels

• Individuals who have a familial history of cardiovascular disease, stroke, or thrombosis

• Individuals who are candidates for long-term methotrexate therapy

It is not a regular practice for a doctor to prescribe MTHFR genotyping test. But for an individual with high levels of homocysteine, it is a smart choice.

Find Out More

For more information regarding SpectraCell MTHFR Genotyping, arrange a consultation by contacting the office of Dr. Kevin Light, an expert in bioidentical hormone therapy, nutrition, and fitness.