According to the American Cancer Society and the CDC (Center for Disease Control and Prevention), colorectal cancer is one of the leading causes of cancer-related deaths in the United States. On average, over one in twenty people develop this condition in their lifetime. Although most of the incidences are sporadic, research has proven that close to five percent of the cases stem from hereditary changes in single genes.

What Is ColoTrue?

Colon cancer usually develops when the cells in the large intestine start to grow out of control. It is also referred to as colorectal cancer, as it can occur in the colon and its lowest section, the rectum. ColoTrue is a cancer panel that is designed to detect colorectal cancer in individuals with a family history of the disease. The panel includes complete sequencing and duplication/deletion analysis of all the 14 genes involved in the disease. If there is a pathogenic variant in any of the 14 genes, then the patient is at increased risk of colorectal cancer.

How Can You Order It?

You will need to bring your medical history to check if you are eligible for this panel. If you are eligible for the test, your blood sample or saliva will be collected and analyzed in a CAP-accredited and CLIA-certified laboratory. Your personalized results will be available for perusal in two or three weeks.

Test Results

The test is designed to look for gene mutations that can cause colon cancer. Although a lot of people who get colon cancer don’t have mutated genes, having a mutation does significantly increase your risk of contracting colon cancer. If you get a positive result, you should look into preventative measures that will help you stave off the disease.


You have to understand that despite the reliability of the blood test, it is not 100 percent accurate. The test can’t tell whether or when you will contract colon cancer. If you test negative for the genes, that does not mean that you will never get colon cancer. It just means that you stand the same chance of contracting the disease as the average person. There are a number of different genetic mutations that can lead to HNPCC or FAP. Genetic testing cannot find all of them. You can have a normal test and still have increased chances of getting colon cancer.

Should You Get Tested?

The decision to get tested for colon cancer is a personal one. You might have financial, emotional, and familial reasons for not wanting to take the test. Also, if you have a positive result, you might have trouble getting life insurance or disability insurance. On the other hand, if you have a family history of colon cancer or a personal history of more than 15 colon polyps, you are much better off getting tested. In such cases, the benefits undoubtedly outweigh the risks.

Schedule a Consultation

Dr. Kevin Light, an expert in bioidentical hormone therapy, nutrition, and fitness, will be able to help you decide whether or not the ColoTrue colon cancer screening is right for you. Contact our office today to schedule your appointment for a consultation.